Montpellier platform

IRMB (Université de Montpellier, Inserm U1183)


Inserm Unité 844 - UM1
Equipe Inserm - ECF- Montpellier

Research topic

The ECELLFRANCE Montpellier platform conducts research on the immunomodulatory and regenerative properties of adult mesenchymal stem cells (MSC) and on their therapeutic use in autoimmune and osteo-articular pathologies.

 

Expertise

  • Mouse models of rheumatoid arthritis, osteoarthritis, scleroderma, (implementation and follow-up of the models, cell therapy treatment, immune response)
  • 3D imaging on live animal by MicroCT analyses
  • Immunomonitoring on MSCs biological effects on recipient immune response
  • Clinical research

Facilities

  • MSC/ASC cell culture of different species (human, murine, equine, ovine) and from different tissue source 
  • Rodents housing facility
  • Imaging platform (high resolution X-ray microtomography for small animal, confocal laser scanning microscopy) 
  • Molecular biology platform 
  • Histology core facility 
  • Multichromatic Flow Cytometry facility (analysis, cell sorting)
  • Biochemistry platform

Keywords

Mesenchymal stem cells (MSC), adipose-derived stromal cells (ASC), chondrocytes, cell differentiation, immunomonitoring , osteo-articular and autoimmune diseases.