With its significant contributions in over 20 national and European clinical trial programs using mesenchymal stem cells (MSC), ECellFrance has acquired a large
amount of data, experience, models, and tools specific to preclinical study of MSC-based products.
The preclinical platforms gather the knowhow, data and tools for biodistribution and toxicology studies specific to MSC. They are located in Montpellier, Toulouse, Clamart, and Grenoble. Each platform has its specificities in terms of equipments and fields of expertise to address, altogether, a wide range of possible applications.
Validated animal models
Evaluation administration routes, clinical and histological monitoring in animals
GLP accreditation for biodistribution and toxicology studies
Data on biodistribution and pharmacokinetic studies using GLP grade bone-marrow or adipose tissue-derived MSC, after local or systemic injection in immunodeficient mice (list of available pharmacokinetics and toxicology data)
Requests for support (service provision or research agreement) can be submitted by filling the online submission form
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